Monoclonal antibodies against LDL further enhance macrophage uptake of LDL aggregates.
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منابع مشابه
Monoclonal antibodies against LDL further enhance macrophage uptake of LDL aggregates.
Self-aggregates of low density lipoprotein (LDL) are taken up and degraded more rapidly by macrophages than is native LDL. That enhanced uptake is attributable in part to phagocytosis via the LDL receptor pathway. However, arterial macrophages appear to express little LDL receptor activity. The present studies demonstrate an alternative mechanism by which LDL aggregates could contribute to foam...
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ژورنال
عنوان ژورنال: Arteriosclerosis and Thrombosis: A Journal of Vascular Biology
سال: 1992
ISSN: 1049-8834
DOI: 10.1161/01.atv.12.11.1258